| 1 | 1988 | Game titleAltered Beast (set 8) (8751 317-0078) | Game makerSega | 10 | 96,590 |
| 2 | 1988 | Game titleSplatterhouse (World, new version (SH3)) | Game makerNamco | 3 | 85,066 |
| 3 | 1988 | Game titleGhouls'n Ghosts (World) | Game makerCapcom | 4 | 74,088 |
| 4 | 1988 | Game titleWonder Boy III - Monster Lair (set 6, World, System 16B) (8751 317-0098) | Game makerWest One | 7 | 16,522 |
| 5 | 1988 | Game titleKitten Kaboodle | Game makerKonami | 2 | 13,777 |
| 6 | 1988 | Game titleImage Fight (World) | Game makerIrem | 3 | 11,922 |
| 7 | 1988 | Game titlePhelios | Game makerNamco | 2 | 10,196 |
| 8 | 1988 | Game titleOrdyne (World) | Game makerNamco | 3 | 7,062 |
| 9 | 1988 | Game titleAssault (Rev B) | Game makerNamco | 3 | 6,679 |
| 10 | 1988 | Game titleP-47: The Phantom Fighter (World) | Game makerJaleco | 5 | 6,406 |
| 11 | 1988 | Game titleFinal Blow (World) | Game makerTaito | 3 | 5,919 |
| 12 | 1988 | Game titleMirai Ninja (Japan, set 1) | Game makerNamco | 2 | 4,758 |
| 13 | 1988 | Game titleMetal Hawk (Rev C) | Game makerNamco | 2 | 4,615 |
| 14 | 1988 | Game titleLegend of Makai (World) | Game makerJaleco | 2 | 2,990 |
| 15 | 1988 | Game titleShingen Samurai-Fighter (Japan, English) | Game makerJaleco | 2 | 1,945 |
| 16 | 1988 | Game titleFace Off (Japan 2 Players) | Game makerNamco | 1 | 1,504 |
| 17 | 1988 | Game titleNinja Kazan (World) | Game makerJaleco | 3 | 1,219 |
| 18 | 1988 | Game titleAce Attacker (FD1094 317-0059) | Game makerSega | 1 | — |
| 19 | 1988 | Game titleBakutotsu Kijuutei | Game makerNamco | 1 | — |
| 20 | 1988 | Game titleChou Zetsurinjin Berabowman (Japan, Rev C) | Game makerNamco | 2 | — |
| 21 | 1988 | Game titleDynamite Dux (set 3, World) (FD1094 317-0096) | Game makerSega | 5 | — |
| 22 | 1988 | Game titleExcite League (FD1094 317-0079) | Game makerSega | 2 | — |
| 23 | 1988 | Game titleForgotten Worlds (World, newer) | Game makerCapcom | 10 | — |
| 24 | 1988 | Game titleKick Off: Jaleco Cup (Japan) | Game makerJaleco | 2 | — |
| 25 | 1988 | Game titleMarchen Maze (Japan) | Game makerNamco | 2 | — |
| 26 | 1988 | Game titleNinja Spirit (World) | Game makerIrem | 2 | — |
| 27 | 1988 | Game titlePassing Shot (World, 2 Players) (FD1094 317-0080) | Game makerSega | 7 | — |
| 28 | 1988 | Game titlePro Tennis World Court (Japan) | Game makerNamco | 1 | — |
| 29 | 1988 | Game titlePro Yakyuu World Stadium (Japan) | Game makerNamco | 3 | — |
| 30 | 1988 | Game titleSukeban Jansi Ryuko (set 2, System 16B, FD1089B 317-5021) | Game makerWhite Board | 1 | — |
| 31 | 1988 | Game titleUfo Senshi Yohko Chan (MC-8123, 317-0064) | Game makerSega | 2 | — |
| 32 | 1988 | Game titleVs. Freedom Force | Game makerSunsoft | 1 | — |